Together, we aspire to deliver ever better health outcomes for patients while lowering overall healthcare costs. Our goal is to compel the customer to act on behalf of their patients while showing great commitment to the rare disease community, whose support is key. The Portfolio Operations Manager is responsible for the operating system that allows CE to evaluate, prioritize, sequence, and govern enterprise work as one portfolio. The manager partners with CE Leadership, Enterprise Operations, Regions, HEDs, RBO teams, and other stakeholders to ensure the organization focuses resources on the work that matters most and can make transparent portfolio decisions when priorities compete. Maintain the integrated CE enterprise portfolio across initiatives, launches, RBO work, and field-partner commitments. Route approved work to the appropriate Enterprise Operations manager, lead, or enabling team for execution. Manage the portfolio governance cadence and prepare decision materials for CE Leadership and CELT as needed. Ensure governance focuses on material decisions, risks, and dependencies rather than routine status reporting. Surface cross-portfolio risks and constraints early enough to enable leadership action. Partner with Enterprise Initiatives and Launch Operations to resolve conflicts and coordinate shared resources. Lead, coach, and develop Enterprise Operations Leads assigned to portfolio and RBO work. Set standards for portfolio data quality, governance materials, decision support, and milestone tracking. Build strong portfolio management capabilities, tools, and ways of working across the team. Contribute to common Enterprise Operations standards, talent practices, and continuous improvement. Portfolio governance calendar and decision materials Integrated dependency, risk, and milestone view Strong drive for results with an enterprise and customer mindset Bachelor's degree required ~8-10 years of pharmaceutical, biotechnology, consulting, commercial, portfolio, strategy, program management, and/or operations experience including leading, coaching or mentoring others strongly preferred ~ Demonstrated experience with portfolio management, prioritization, governance, or resource planning ~ Strong analytical, synthesis, and project/program management capabilities ~ Ability and willingness to travel as required for internal and external business meetings Graduate-level degree (e.g., MBA or advanced life sciences degree) Prior commercial operations, portfolio management, strategy, or transformation experience Experience supporting large-scale field organizations, RBO, or enterprise planning processes Location: This position can be based in SSF or Remote. Relocation benefits are not available. A discretionary annual bonus may be available based on individual and Company performance. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.